About Zocor: dosage and contraindications

Generic Zocor should be used under control of your doctor. Although the drug is really safe and effective for most patients. Typically, the initial dose of generic Zocor is 10mg 1 time/evening. In mild or moderate hypercholesterolemia starting dose is 5mg/day.

If necessary, it is possible to use increase the dose, following 4-week intervals. The maximum daily dose - 80mg. If the LDL level is below 75mg / dL (1.94 mmol / l) or plasma total cholesterol is below 140mg / dL (3.6 mmol / l) the dose of Zocor should be reduced.

In CHD Zocor is administered in an initial dose of 20mg 1 time/evening. Correction of the dosage, if necessary, should be the same as in hypercholesterolemia.

Patients receiving cyclosporine, fibrates, nicotinic acid with Zocor, the maximum recommended dose is 10mg/day.

Since Zocor excreted by the kidneys in small numbers, there is no need to change the dose in patients with moderate renal impairment. In patients with severe renal impairment (creatinine clearance less than 30 ml / min) should carefully evaluate the advisability of appointing a drug at a dose exceeding 10mg/day. If this dose is considered necessary, should receive it with caution.

Contraindications to the use of Zocor drug:

Cancelation of lipid-lowering drugs during pregnancy should not have a material impact on long-term treatment of primary hypercholesterolemia. In addition, cholesterol and other products of its biosynthesis play an important role in fetal development, including synthesis of steroids and cell membranes. Due to the fact that Zocor inhibits the synthesis of cholesterol and possibly other products of its biosynthesis, the drug may have adverse effects on the fetus when it is assigned to pregnant women.

Women of childbearing age who take Zocor should avoid conception. If in the course of treatment with Zocor arises pregnancy, the drug therapy should be stopped and the woman should be informed about possible danger to the fetus.